The Nolini (Lepidoptera, Noctuidae sensu lato, Nolinae, Nolini) of Africa, Madagascar and the Western Palaearctic Region are reviewed and described. Their status and relationships are discussed in diagnoses of each genus, subgenus or species. The treatment covers 427 species distributed over 8 genera. For each species type specimen, type series and all available specimens, distributed over numerous museums and private collections, have been checked. A diagnosis and the geographical range are given, and where known, habitat preference and biology. All species are presented with their full name and references to the original description, fully referenced synonyms; special emphasis is given to the descriptions of genitalic features. For each species colour photos of adults, figures of male and female genitalia, and in many cases distribution maps are provided. For a complete list and synopsis of all specific taxa of Africa, Madagascar and the Western Palaearctic Region see the Checklist of species/subspecies/species-groups given at the beginning of the specific treatment. Descriptions of 2 genera, 2 subgenera, 253 species and 14 subspecies are given.